A joke game based on this bible verse: Again I tell you, it is easier for a camel to go through the eye of a needle than for someone who is rich to enter the kingdom of God."

A collection of four "virtual pets": ISO Baby ISO Cat ISO Pig ISO Sheep

LAZlife is an early (B&W) game of life simulation that offers a couple settings to play with.  You can set the simulation speed, resolution (very high resolution can be achieved) and the shape of the life bits.  

Life and Death is a computer game published in 1988 by The Software Toolworks. It is one of the few realistic medical computer games ever released. In the role of a resident abdominal surgeon at fictional hospital...

A colored version of John Conway's Game of Life with a few improvements over  older versions. The new cells are displayed in green, the rules for birth and death can be changed, and the board wraps around the screen's borders.

LifeMaker is a cellular automata program for color Macs. Cellular automata (CA) can be thought of as mini-universes. The universe starts at some initial state and evolves according to a simple local rule. ConwayUs Game of Life is by far the best...

MacChallenger is a simulation of landing the Space Shuttle.  The parameters (glide slope, stall speeds etc.) were based on Nasa documents.  Unique features (Version 2) include an autopilot, weather, and an "after action" video...